Postcaesarean open-heart surgery for Streptococcus sanguinis infective endocarditis

The Streptococcus sanguinis Competence Regulon Is Not Required for Infective Endocarditis Virulence in a Rabbit Model

Streptococcus sanguinis is an important component of dental plaque and a leading cause of infective endocarditis. Genetic competence in S. sanguinis requires a quorum sensing system encoded by the early comCDE genes, as well as late genes controlled by the alternative sigma factor, ComX. Previous studies of Streptococcus pneumoniae and Streptococcus mutans have identified functions for the >100...

Surgery for Infective Endocarditis

Endocarditis complicating open-heart surgery.

BACTERIAL ENDOCARDITIS following intracardiac surgery for congenital defects with use of extracorporeal circulation is a new entity, as old only as open intracardiac surgery. The reported experience is therefore meager. Suggestions regarding its pathogenesis, recognition, behavior, management, and prevention are few. Heins and Lindel reported five cases of bacterial endocarditis in a series of ...

Radial mycotic aneurysm complicated with infective endocarditis caused by Streptococcus sanguinis.

Peripheral mycotic aneurysm is a rare complication of infective endocarditis. We herein report the case of a 61-year-old man with a mycotic aneurysm in the left brachial artery, that appeared during treatment with antibiotics against infective endocarditis caused by Streptococcus sanguinis. After confirming the collateral blood flow on arteriography, we resected the aneurysm and performed valvu...

Streptococcus agalactiae mural infective endocarditis in a structurally normal heart

A 38-year-old Caucasian man with uncontrolled diabetes mellitus type 2 was admitted with a 1-week duration of fevers, chills, and a non-productive cough. He had a left ischiorectal abscess 1 month prior to admission. Physical examination revealed caries on a left upper molar and a well-healed scar on the left buttock, but no heart murmur or evidence of micro-emboli. Blood cultures grew Streptoc...